Sandbox29

1EVE
'''This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!'''

Created by Lori Mathis

1eve is a protein that is a drug used to prevent Alzheimer disease. The overall structure of 1EVE contains 2 types of amphipathic elements; 15 beta sheets and 16 alpha helices. 1eve is a fairly standard molecule in the sense that the hydrophic aspects of the protein are well-maintained on the inside, while the hydrophillic portions are around the outside. 1eve has an active name called Acetylcholinesterase, which has a ligand called Aricept. There is an active site in the middle of the molecule. 1eve is considered an AChE inhibitor, in which it has a high affinity for. The overall protein itself was created by a Japanese corporation called the Eisai Company.

Reference to the Proteopedia pages dedicated to 1EVE, contributors are Eran Hodis, Joel L. Sussman, OCA, Wayne Decatur